What is Binswanger's disease/Subcortical vascular dementia?

Binswanger's disease, also known as Subcortical vascular dementia, affects the deeper brain regions. Signs include slower thinking, memory loss, and personality changes, which are often caused by diseases such as Parkinson's or Huntington's.

A progressive loss of memory, thinking, reasoning, and the ability to care for oneself is referred to as dementia. It occurs when neurons in the brain, which are considered brain cells, become diseased and die. The symptoms experienced by the person depend on the areas of the brain affected.

Subcortical dementias affect areas deep within the brain, such as the thalamus and basal ganglia. Motivation, emotional control, sensory processing, and much more involve these areas, as well as many other cognitive processes.

What are the signs of Binswanger's disease?

Binswanger's disease can cause various symptoms. However, the symptoms depend on the disease you have, and which parts of the brain are affected.

Here are some symptoms of Binswanger's disease:

  • Apathy, depression, and mood or personality changes
  • Executive function impairment
  • Memory impairment and forgetfulness
  • Quiet, slurred, or slow speech, confusion, and slowed thinking

Movement symptoms often occur simultaneously with Binswanger's disease, such as:

  • Muscular contractions
  • Tremors
  • Difficulty in walking

What are the subtypes of subcortical dementia?

Binswanger's disease is caused by various diseases. The following diseases are most associated with subcortical dementia:

  • Parkinson's disease
  • Huntington's disease
  • Vascular dementia
  • Lewy body dementia
  • Multiple system atrophy, multiple sclerosis, and neurosyphilis
  • Progressive palsy of the supranuclear
  • Dementia associated with HIV

What causes Binswanger's disease?

Typically, people with subcortical dementia have one or more of the above problems. However, each illness has a somewhat different process that causes dementia.

For example, in vascular dementia, tiny blood vessels in the brain get hardened, making it harder for blood to get to subcortical areas such as the amygdala. This might lead to small strokes throughout the subcortical region that cause atrophy and signs of dementia.

Alpha-synuclein, a protein, aggregates in subcortical tissues such as the substantia nigra during Parkinson's disease by forming big clusters known as Lewy bodies. Lewy bodies disable brain activity and lead to malfunctioning or dead neurons.

Who is at risk for Binswanger's disease?

Dementia can be caused by your age, gender, and family history. According to a study, other risk factors proposed by studies are:

  • Depression
  • Head injury due to diabetes
  • Hearing loss
  • Alcoholism
  • Hypertension, obesity, and low educational background
  • Lack of exercise and smoking
  • Social isolation

You may also be more vulnerable to subcortical dementia if you have another neurological disorder.

How do doctors diagnose Binswanger's disease?

Subcortical dementia is not a diagnosis. It is simply a catchall term for dementia that affects a specific area of the brain.

A doctor or other healthcare provider needs to perform a brain scan to identify where parts of your brain are affected before they can decide whether you have subcortical dementia. MRIs, CT scans, and PET scans are some of the types of brain scans used in diagnosing dementia.

A doctor will try to identify the cause of any dementia symptoms you are experiencing. The following will be part of the diagnostic process:

  • A review of your medical history
  • A physical examination
  • Questions regarding your symptoms that you or a close relative can answer

Lab tests and cognitive evaluations are other commonly used tests for dementia.

How can Binswanger's disease be treated?

The course of treatment is determined by the underlying cause of Binswanger's disease.

For example, if you have subcortical vascular dementia, your physician might advise treatments to help boost blood flow to the brain regions that are affected. These can include certain lifestyle changes or drugs for hypertension.

Even though most disorders that cause subcortical dementia cannot be treated, treatments can often slow the advancement of the disease.

If you have symptoms of any type of dementia, you must seek treatment as soon as possible.

How long does a person with Binswanger's disease expect to live?

A variety of factors can affect your life expectancy if you have Binswanger's disease. These include your age, general health, and the underlying disease.

For example, a study reported that the average life expectancy for a patient with vascular dementia is about 3–5 years from the time symptoms first appear.

A study reported that the average survival after the onset of dementia from Parkinson's disease was 2.5 years less than in people with Parkinson's disease without dementia.

Why choose Tender Palm Super-Speciality Hospital for Binswanger's Disease treatment in Lucknow, India?

Tender Palm Super-Speciality Hospital offers advanced Binswanger's Disease treatment in Lucknow, India, at an affordable cost. We have a team of experienced neurologists, geriatric specialists, and vascular medicine experts who provide accurate diagnosis with advanced MRI imaging, neuropsychological assessments, and comprehensive cerebrovascular evaluations, personalized medical care, and holistic treatment plans including vascular risk factor management, cognitive rehabilitation, and neuroprotective therapy. Our Neurology and Geriatric Care team has decades of experience in successfully treating Binswanger's Disease in Lucknow, India.

To seek an Expert Consultation for Binswanger's Disease treatment in Lucknow, India:

Call us at +91-9076972161
Email at care@tenderpalm.com

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Our Experts

Dr. Rohit Rao Pushkar
Dr. Rohit Rao Pushkar
Senior Consultant - Neurology

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