What is a Demyelinating Disease?

A demyelinating disease is a condition that damages the myelin in your brain, spinal cord, and nerves. Myelin is a protective cover, or sheath, around the body section of nerve cells called axons. It fortifies, protects, and insulates your nerve cells and allows electrical impulses to travel between cells.

In demyelinating diseases, the immune system starts attacking the myelin sheath or cells that make up myelin. This is actually what causes nerve signal communication and function to change along with the symptoms.

What are the types of demyelinating diseases?

Common types of demyelinating diseases primarily affect the central nervous system consists of the brain and spinal cord. This also includes:

  • Multiple Sclerosis.
  • Neuromyelitis Optica Spectrum Disorder (NMOSD).
  • Transverse myelitis (TM).
  • Acute disseminated encephalomyelitis (ADEM).
  • Progressive multifocal leukoencephalopathy (PML).
  • Central pontine myelinolysis (osmotic demyelination syndrome).
Common demyelinating disorders affecting your peripheral nervous system (nerves outside of your brain and spinal cord) include:
  • Charcot-Marie-Tooth disorder (CMT).
  • Guillain-Barré Syndrome (GBS).
  • Chronic inflammatory demyelinating polyneuropathy, or CIDP.

What are the symptoms of a demyelinating disease?

The signs and symptoms of demyelinating illnesses vary according to the type. Common signs of a central nervous system demyelinating illness can include:

  • Vision changes include fuzzy vision, decreased colour vision, eye movement pain, or double vision.
  • Tingling or numbness in many regions of the body.
  • MS hug is also known as a squeezing sensation around the chest or abdomen.
  • Fatigue.
  • Bladder or bowel issues, such as difficulty (or hesitancy) in peeing or a sense of urgency (as in, when you have to go, you must go).
  • When you bend your neck forward, you may experience electrical tingling or shocks down your back, arms, or legs.
  • Having difficulty walking.
  • Muscle fatigue or stiffness.

You may have symptoms that impact only one region of your body or several simultaneously. Symptoms may vary in severity. This means they may worsen (feel more acute) before gradually improving.

What causes a demyelinating disease?

Demyelinating diseases result from the destruction of myelin and cells that form myelin. When your immune system accidentally attacks healthy myelin in your body, your myelin and cells are damaged. Your immune system protects your body against causes of illness, which include bacteria and viruses. Sometimes, your immune system fails to receive the right instructions and will mistakenly identify your myelin cells as those of something destructive to your body. When this occurs, it results in inflammation, leading to symptoms of demyelinating diseases.

A demyelinating disease can result from multiple causes. These include;

  • A viral or bacterial infection
  • Genetic predisposition (mutations in your DNA) that make someone prone to an autoimmune condition
  • Other conditions such as vitamin deficiencies

In some cases, the cause remains unknown. Current research is ongoing to increase knowledge about demyelinating diseases.

How is a demyelinating disease diagnosed?

Your medical provider will review your symptoms during a physical examination and take a complete medical history. If they suspect that you have a demyelinating disease, they may refer you to a neurologist, a doctor who specialises in nervous system disorders.

The neurologist will do a neurological examination and tests. There is no single test to diagnose demyelination. Your provider may employ one or more of the following tests to rule out possible illnesses with similar symptoms before making a diagnosis:

  • A magnetic resonance imaging (MRI) scan.
  • A lumbar puncture (or spinal tap).
  • Optical coherence tomography (OCT).
  • EMG (Electromyography).
  • There are blood tests.
  • Test for evoked potentials.

How is a demyelinating disease treated?

The treatment for a demyelinating disease will vary depending on your condition. Your medical professional will work with you to try to manage the symptoms and sometimes to alter the course or progress of the disease within your body. Treatment could include:

  • Medications.
  • Physiological and/or occupational treatment.
  • Your medical professional will assess your symptoms and determine the best treatment strategy. Before you start therapy, ask about the adverse effects and what to expect. If you experience new or worsening symptoms after beginning therapy, notify your healthcare professional. Treatment is usually most successful when it begins early.

What’s the outlook or prognosis for a demyelinating disease?

Your chances depend on the sort of demyelinating disease that triggered your symptoms. These disorders impact many elements of your life, including your thoughts, movements, and emotions. You may have difficulty walking or with your daily routine, for example. Many require assistance at home so that they may be able to live in a safe environment. Some people's symptoms are mild, with no long-term effect. For others, their symptoms may be severe, making it almost impossible to have a normal daily life. No two cases are the same. Your doctor will work with you to manage your symptoms throughout your life since demyelinating diseases are incurable.

How long do people live with a demyelinating disease?

Many demyelinating diseases do not necessarily impact your overall life expectancy; however, the condition can significantly alter your way of life. In general, patients with a demyelinating disease live a few years fewer than those individuals who don't have this condition. Your life span is determined by the amount of nerve damage you sustain. This is not the same for everyone. Your healthcare provider will be able to give you a more accurate answer about this, given your condition.

When should I seek medical care?

Call your medical professional if you have any of these symptoms of demyelinating disease:

  • Vision changes.
  • Tingling or numbness.
  • Fatigue
  • Bladder or bowel problems.
  • Trouble walking.
  • Stiff or weak muscles.

Why choose Tender Palm Super-Speciality Hospital for Demyelinating Diseases Treatment in Lucknow, India?

Tender Palm Super-Speciality Hospital offers advanced Demyelinating Diseases treatment in Lucknow, India, at an affordable cost. We have a team of experienced neurologists and neuroimmunology specialists who provide accurate diagnosis and both medication and immunotherapy-based treatment options including disease-modifying therapies, relapse management, and neuroprotective procedures. Our Neurology and Neuroimmunology team has decades of experience in successfully treating Demyelinating Diseases in Lucknow, India.

To seek an Expert Consultation for Demyelinating Diseases Treatment in Lucknow, India:

Call us at +91-9076972161
Email at care@tenderpalm.com

Request an Appointment
Mon - Sat 9:00 AM to 6:00 PM IST

Our Experts

Awards & Accreditations