What is Esthesioneuroblastoma?

Esthesioneuroblastoma (es-THEE-zee-oh-NOOR-oh-blas-TOH-muh) is a rare form of head and neck cancer. Doctors sometimes refer to it as olfactory neuroblastoma. In esthesioneuroblastoma, you have cancerous tumors in your nasal cavities, which are hollow areas inside your nose. The tumors affect nerves and tissues responsible for your sense of smell.

This condition primarily occurs in adults, but it can occur in children and adolescents. It is treated by healthcare providers through surgery to remove the tumor, followed by radiation therapy. Esthesioneuroblastoma may recur, so healthcare providers advise people to have regular checkups to confirm that it hasn't recurred.

What are the symptoms of esthesioneuroblastoma?

It may make you feel like you have a sinus infection or other sinus issues, including:

• Anosmia (loss of sense of smell).
• Nasal congestion (stuffy nose).
• Recurrent epistaxis (nosebleeds).

What causes esthesioneuroblastoma?

There is no known cause for this condition. Researchers are studying possible chromosomal changes or mutations that may be involved in causing esthesioneuroblastoma.

How is esthesioneuroblastoma diagnosed?

Healthcare providers may diagnose it by doing various imaging tests and, if appropriate, a biopsy. Imaging tests may include:

• Computed tomography (CT) scan.
• Magnetic resonance imaging (MRI) scan.
• Nasal endoscopy.
• Positron emission tomography (PET) scan.

What are the stages of esthesioneuroblastoma?

Healthcare providers use cancer staging systems to plan treatment and a prognosis. Esthesioneuroblastoma stages are:

• Stage A: Cancerous cells develop into a tumor in your nasal cavity.
• Stage B: The cancer spreads directly from your nasal cavity to your nasal sinuses.
• Stage C: The tumor spreads directly from your nasal cavity and sinuses towards your eyes or your brain.
• Stage D: Tests reveal that cancerous tumors have spread to other parts of your body, like the lymph nodes in your neck, your bone marrow, or your lungs.

What are the treatments for esthesioneuroblastoma?

Healthcare providers often operate to remove cancerous tumors. They may do:

• Endoscopic surgery.
• Craniofacial surgery.
• Craniotomy

Other treatments are:

• Radiation therapy to kill any remaining cancerous cells after surgery.
• Chemotherapy to treat esthesioneuroblastoma if tumors can't be safely removed with surgery.

How long does it take to recover from esthesioneuroblastoma surgery?

That depends on the kind of surgery you have, but people stay in the hospital for two to five days before recovering at home. It may be one to two months before they get radiation therapy.

What are the treatment side effects?

Surgery, radiation therapy, and chemotherapy have varying side effects:

• Side effects of surgery include pain, nasal stuffiness, and reaction to anesthesia
• Common side effects of chemotherapy and radiation include body fatigue, diarrhea, nausea, and vomiting.

What are the complications of treatment?

• Possible complications of surgery may be:
• Infection
• Excessive blood loss.
• Permanent loss of smell. There is tight coordination between your sense of smell and your sense of taste. Thus, you might also lose your taste.
• Cerebrospinal fluid (CSF) leak.
• Drainage in your nose that may feel crusty and dry.

What are the complications of esthesioneuroblastoma?

Recurrent esthesioneuroblastoma often comes back after treatment and may come back years after you've finished treatment. It may come back in the original site or in nearby tissue, and it rarely comes back in more distant areas of your body.

The prognosis is generally poor without treatment, as it can spread (metastasize) to the brain or other parts of the body. According to the literature, esthesioneuroblastoma most frequently spreads to the sinuses but may also spread to lymph nodes in the neck, lungs, and bones.

What is the prognosis for esthesioneuroblastoma in adults?

Your prognosis (outlook) is your provider's estimate of how a disease will affect you after treatment. Every person is different, and prognosis will depend on several factors, like:

• Where the tumor is in your body.
• If cancer has spread to other areas of your body.

What percentage of the tumor was removed during the surgery?

Results of lab analysis that show tumor cell features.

If you have questions about your prognosis, discuss them with your surgeon and other care team members. They know you and your situation and are your best source of information.

What is the prognosis for esthesioneuroblastoma in children?

As with adults, the prognosis depends on the child's specific situation, including factors such as the tumor location, particular features of tumor cells, whether the tumor has spread, and the extent of tumor removal during surgery.

What is the survival rate of esthesioneuroblastoma?

Healthcare providers estimate the survival rate based on the experiences of those who possess the condition. In this regard, 50% to 90% of the individuals with the condition survived after five years following the diagnosis.

Trying to figure out what survival rate data is saying can be confusing and stressful. Survival rates are estimates based on other people's experiences. What was true for them may not be true for you. If you have questions, don't hesitate to talk with your provider. They'll explain survival rate estimates and how those estimates factor into your situation.

Is esthesioneuroblastoma fatal?

It can. Esthesioneuroblastoma can grow into your lungs or other parts of your body. It may come back after treatment and can form in different places. If the metastatic or recurrent esthesioneuroblastoma isn't diagnosed, it may become life-threatening. This is why checkups are necessary so your provider can take imaging and other diagnostic studies that could reveal the cancer in the early stages.

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When should I see my doctor?

Esthesioneuroblastoma can recur, so you should anticipate seeing your care team at least annually for the rest of your life. Your team will monitor your overall health. They may perform imaging tests to look for signs of recurrent esthesioneuroblastoma.

Why choose Tender Palm Super-Speciality Hospital for Esthesioneuroblastoma Treatment in Lucknow, India?

Tender Palm Super-Speciality Hospital offers advanced Esthesioneuroblastoma treatment in Lucknow, India, at an affordable cost. We have a team of experienced neurosurgeons and neuro-oncology specialists who provide accurate diagnosis and both surgical and non-surgical treatment options including endoscopic tumor resection, radiation therapy, and chemotherapy procedures. Our Neurosurgery and Neuro-Oncology team has decades of experience in successfully treating Esthesioneuroblastoma in Lucknow, India.

To seek an Expert Consultation for Esthesioneuroblastoma Treatment in Lucknow, India:

Call us at +91-9076972161
Email at care@tenderpalm.com

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