What is Myxofibrosarcoma?

Myxofibrosarcoma (MFS) is a form of soft tissue sarcoma cancer in which the starting point is connective tissue. It comprises structures like bones, cartilage, and fat that give your organs structure and protection. MFS generally grows in the arm or leg and can resemble a small lump

Myxofibrosarcoma typically starts growing in connective tissues under your skin, but it may also begin in deeper connective tissues around your muscles.

MFS is a fast-growing tumor that spreads quickly to other parts of your body. It is more likely to come back after treatment compared to other types of cancer.

Who might get myxofibrosarcoma?

Myxofibrosarcoma is more common in adults older than 50 years and a bit more common in people assigned male at birth (AMAB) than in people assigned female at birth (AFAB).

Other risk factors that may contribute to your risk of malignant soft tissue tumors, such as MFS, include:

  • Genetics: Some genetic disorders may increase your risk for soft tissue sarcomas.
  • Environmental exposures: Exposure to certain chemicals, including arsenic and herbicides, may increase your risk.
  • Radiation therapy: Radiation exposure is believed to raise your potential for some cancers, including myxofibrosarcoma.

What are the symptoms of myxofibrosarcoma?

When myxofibrosarcoma starts, you might not have any symptoms. When it grows, you can feel a lump under your skin. A tumor often presents painless, but you will have discomfort and swelling.

What causes myxofibrosarcoma?

Experts do not know the cause of myxofibrosarcoma. As is true for every other type of cancer, it forms when a mutation occurs in the DNA of the cells. The DNA change instructs the cells to multiply, forming a disorganized mass known as a tumor.

How is myxofibrosarcoma diagnosed?

Myxofibrosarcoma can be tricky to diagnose as it can be mistaken for another type of growth. Your healthcare provider may ask if the mass has grown since you first noticed it.

To determine if you have MFS or another type of growth, your healthcare provider may do:

Imaging tests like CT or MRI scans check if the growth has reached your deep muscle tissues. A needle or open biopsy takes a small sample of the growth to be examined in a lab. A chest X-ray looks for signs that the cancer has spread to your lungs. If MFS spreads, it is most likely to go to your lungs.

Your doctor will surgically remove the tumor and a small amount of the surrounding tissue. You might have radiation therapy before or after surgery. This therapy can help shrink the tumor or reduce the chance of it coming back. Doctors usually do not use chemotherapy for myxofibrosarcoma as often as they do for other types of cancer.

The treatment for myxofibrosarcoma depends on several factors, including:

  • Grade: A low-grade myxofibrosarcoma is usually only treated with surgery. If you have a high-grade myxofibrosarcoma, you will have surgery plus other treatments such as radiation therapy.
  • Stage: The staging tells healthcare providers how much cancer has spread. The higher the stage, the more that cancer has spread throughout your body. Higher-stage myxofibrosarcoma tends to require surgery plus other treatments.
  • Size: If the tumor is smaller than 2 inches (about 5 centimeters), surgery is likely your only treatment. For larger tumors, you might also need radiation therapy.
  • Depth: If the tumor reaches deeper tissues, like between your muscles, you may need both surgery and radiation therapy.

Will I need amputation to treat myxofibrosarcoma?

No. Myxofibrosarcoma was once commonly treated by removing the arm or leg (amputation). Now, doctors and other healthcare providers do everything possible to avoid amputation.

How can I lower my chances of getting myxofibrosarcoma?

There is no known way to prevent myxofibrosarcoma. With all cancers, healthy lifestyle practices may reduce your risk. You may want to limit as much as possible risk factors, such as radiation or chemical exposure.

What is the prognosis of myxofibrosarcoma?

Myxofibrosarcoma has a higher than other soft tissue sarcomas' prognosis of recurrence following treatment. Up to 1 in 2 people with this type of cancer recurred within five years of their treatment.

Low-grade myxofibrosarcoma is less likely to come back than higher-grade tumors. After treatment, you will have regular follow-up imaging with your healthcare provider. If the tumor does come back, seeing your healthcare provider regularly improves the chances of finding and treating myxofibrosarcoma early.

What is the survival rate for myxofibrosarcoma?

Myxofibrosarcoma is associated with better survival than other soft tissue sarcomas. According to one research, most individuals diagnosed with myxofibrosarcoma survive five years or more following the diagnosis.

Why choose Tender Palm Super-Speciality Hospital for Myxofibrosarcoma treatment in Lucknow, India?

Tender Palm Super-Speciality Hospital offers advanced Myxofibrosarcoma treatment in Lucknow, India, at an affordable cost. We have a team of experienced oncologists, orthopedic oncologists, and cancer surgeons, known as some of the best doctors for treating rare soft tissue sarcomas. We provide accurate diagnosis with advanced imaging and biopsy tests, personalized treatment including surgery, radiation therapy, and chemotherapy when required. Our team has decades of experience in successfully treating Myxofibrosarcoma in Lucknow, India.

To seek an Expert Consultation for Myxofibrosarcoma treatment in Lucknow, India:

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