Pregnancy is often described as one of the most joyful and transformative experiences in a woman's life. However, for a small number of women, this joyful period may become complicated by a serious health challenge- breast cancer diagnosed during pregnancy or shortly after childbirth. When these two life-changing events occur together, patients and their families are often overwhelmed with questions about treatment safety, the health of the unborn baby, and long-term outcomes.
Breast cancer related to pregnancy, also known as pregnancy-associated breast cancer (PABC), has been defined as breast cancer diagnosed during pregnancy, within a year after delivery, or sometimes during breastfeeding. Although it is relatively rare, the number of cases has gradually increased in recent years, largely because more women are choosing to delay pregnancy until their thirties or later, which coincides with a higher age-related risk of breast cancer.
Fortunately, scientific developments in medicine have enabled us to successfully treat breast cancer among pregnant women without harming the fetus. This preparation, combined with the assistance of several medical specialists, will yield positive results for both the patient and her unborn child.
Breast cancer is characterized by abnormal cells growing uncontrollably in the breast, resulting in a mass known as a tumor, which may spread to other areas of the body. Although breast cancer during pregnancy is biologically similar to non-pregnancy-related breast cancer, it is believed that pregnancy hormones may affect the growth of the tumor.
The body produces many hormones during pregnancy, including progesterone and estrogen, which stimulate breast tissue growth in preparation for nursing. These hormonal changes may also stimulate the growth of certain hormone-responsive breast cancer cells.
In addition, the changes in breast tissue due to pregnancy also make diagnosis difficult. with the increased size and density of breast tissue, any unusual development, such as a lump, can be missed due to these changes. The first response to breast changes would be thinking that they are due to pregnancy only.
Even so, early detection remains extremely important. When breast cancer is identified early, treatment options are more effective, and outcomes are generally better.
Pregnancy-associated breast cancer is uncommon, but it is among the most common malignancies found during pregnancy.
Medical studies estimate that breast cancer occurs in approximately 1 in every 3,000 pregnancies. As maternal age at first pregnancy continues to rise globally, healthcare professionals expect the incidence of pregnancy-associated breast cancer to gradually increase.
Although this diagnosis is emotionally daunting, studies have found that with the right therapy, almost all pregnant women diagnosed with breast cancer are capable of giving birth to healthy children, just like any other woman with breast cancer who is not pregnant.
The symptoms of breast cancer in pregnancy are normally similar to those experienced by women who are not pregnant. However, due to normal changes in the breast during pregnancy, symptoms may sometimes be overlooked.
The common symptoms include:
Any occurrence of these symptoms during pregnancy requires immediate attention. Any unusual condition involving the breasts must be assessed by a medical practitioner.
Early evaluation does not harm the pregnancy and can significantly improve treatment outcomes if cancer is present.
The process of diagnosing breast cancer in pregnant women is carried out using safe diagnostic techniques.
The first step in the diagnostic process is a thorough physical examination by a medical practitioner, who assesses the breast and underlying lymph nodes.
Breast ultrasound is the most commonly used imaging test during pregnancy. It is safe for both mother and fetus because it uses sound waves rather than radiation, as it may help determine whether a lump is solid or fluid-filled.
If a mammogram is required in pregnancy, it can still be done. A lead shield will be placed over the baby's abdomen to protect the baby. Mammography is a very low-dose radiation imaging and thus considered relatively safe if medically warranted.
If imaging tests suggest cancer, a biopsy is required to confirm the diagnosis, as a tiny sample of tissue is taken out and inspected under a microscope during this process.
Usually, a core needle biopsy is carried out, using local anesthesia, and is considered safe during pregnancy.
Once cancer is confirmed, further tests help determine the tumor's stage and characteristics.
Once diagnosed, the size of the tumor and whether or not it has spread are determined, which is called the stage of cancer.
Some tests, such as CT scans or PET scans, which may be used to determine the stage of cancer in non-pregnant patients, may not be performed, or alternative tests may be done, which are considered safer during pregnancy.
Tests that may be done to determine whether or not cancer is present include:
Doctors carefully select tests that provide important medical information while minimizing risk to the developing baby.
One of the most common fears among pregnant women diagnosed with breast cancer is whether treatment will harm their baby. Fortunately, depending on the cancer's features and the stage of pregnancy, a number of treatments can be safely given during pregnancy.
In most cases, treatment planning involves the input of various experts, including oncologists, surgeons, obstetricians, radiologists, and pediatricians.
Surgical interventions can be safely done during pregnancy and are usually the primary method of treatment.
Two types of surgery that may be performed include:
Furthermore, a sentinel node lymphatic biopsy may be carried out to check whether cancer has spread to nearby lymph nodes.
During the second and third trimesters of pregnancy, chemotherapy can be administered without risk.
However, chemotherapy is usually avoided during the first trimester, when the baby's organs are still developing, because of a greater possibility of birth abnormalities.
When administered later in pregnancy, many commonly used chemotherapy drugs have been shown to be relatively safe for the fetus, though close monitoring is essential.
Doctors usually stop chemotherapy a few weeks before delivery to allow the mother's blood counts to recover.
Radiation therapy is typically postponed until after delivery because radiation exposure may pose risks to the fetus.
If radiation is required as part of breast-conserving therapy (lumpectomy), it is usually scheduled after the baby is born.
Some treatments commonly used for breast cancer cannot be given during pregnancy.
Hormone therapy drugs such as tamoxifen and certain targeted therapies may harm fetal development and are usually delayed until after childbirth.
In most cases, doctors aim for a full-term pregnancy whenever possible.
Premature delivery is one of the options if there are forms of treatment for the cancer that cannot be done while pregnant. Nevertheless, the present techniques used for cancer treatment guarantee the continuity of the cancer treatment while pregnant, avoiding premature delivery.
Fetal development is closely monitored during cancer treatment.
Breastfeeding decisions depend on the type of treatment being used.
Women undergoing chemotherapy or certain medications are usually advised not to breastfeed, as some drugs can pass into breast milk.
If treatment has been completed and medications are no longer present in the body, breastfeeding may still be possible.
It is recommended that patients discuss their breastfeeding intentions with their oncology and obstetric teams to establish the best option for them.
It is emotionally challenging for a woman diagnosed with cancer while pregnant. A woman diagnosed with cancer while pregnant may feel frightened and concerned about her health and the health of her unborn baby.
Support from health care providers, families, and psychological support is very important.
Counseling, support groups, and patient education programs help women navigate the complex decisions associated with cancer treatment during pregnancy.
Many hospitals offer specialized programs that focus on the emotional and psychological needs of pregnant cancer patients.
Research indicates that when properly treated, women with pregnancy-associated breast cancer can achieve similar survival rates as women with breast cancer of the same stage but not associated with pregnancy.
The most important factors affecting prognosis include:
The most important elements are still prompt identification and prompt treatment in achieving favorable outcomes.
Many women who have been treated for breast cancer later wonder whether it is safe to become pregnant.
Pregnancy following breast cancer therapy does not raise the chance of cancer recurrence in the majority of individuals, according to studies.
Doctors usually recommend waiting at least two years after treatment before attempting pregnancy, as this period carries the highest risk of recurrence.
Women seeking conception after treatment must consult their oncology and fertility experts for guidance on a safe conception strategy.
While it is not possible to prevent breast cancer, awareness and regular self-examinations can help detect any abnormalities.
Pregnant women must:
Early evaluation of suspicious symptoms can significantly improve a patient's outcome.
Tender Palm Super-Speciality Hospital offers advanced Pregnancy with Breast Cancer treatment in Lucknow, India, at an affordable cost. We have a team of experienced breast surgeons and maternal-fetal medicine specialists who provide accurate diagnosis and both non-surgical and surgical treatment options including surgery, chemotherapy, and comprehensive multidisciplinary maternal and fetal care procedures. Our Breast Surgery and Maternal-Fetal Medicine team has decades of experience in successfully treating Pregnancy with Breast Cancer in Lucknow, India.
Call us at +91-9076972161
Email at care@tenderpalm.com