Tumor Marker Testing (AFP, hCG for Testicular Cancer)
Overview
Tumor marker testing is a vital diagnostic tool in the assessment/evaluation, and management of testicular cancer. Cancerous cells release Specific proteins and hormones into the bloodstream, and their measurement helps diagnose, stage, monitor treatment, and detect recurrence. AFP (Alpha-fetoprotein) and HCG (Human Chorionic Gonadotropin) are the key markers for testicular cancer.
This testing is often recommended alongside imaging scans and physical examination to provide a complete understanding of the disease and its progression.
Why is Tumor Marker Testing Needed?
Early Detection: Elevated AFP or hCG can indicate the presence of testicular tumors even before they are clinically evident.
Differentiating Cancer Types: Helps distinguish between different subtypes of germ cell tumors (seminomas vs. non-seminomas).
Treatment Monitoring: Levels decrease as the cancer responds to therapy, guiding oncologists in evaluating the effectiveness of treatment.
Detecting Recurrence: Rising levels after treatment may signal relapse at an early stage.
Prognostic Value: Provides information about the aggressiveness of cancer and helps plan appropriate treatment.
The Process of Tumor Marker Testing
Blood Sample Collection: A simple venipuncture is performed under the supervision of doctors to collect blood.
Laboratory Analysis: The sample undergoes a test for levels of AFP and hCG.
AFP (Alpha-fetoprotein): Elevated in non-seminomatous germ cell tumors but never in pure seminomas.
hCG (Human Chorionic Gonadotropin): Elevated in seminomas and non-seminomatous tumors.
Result Interpretation: Oncologists interpret results in combination with imaging, physical exam, and biopsy findings.
Follow-up Tests are essential to monitor the condition in intervals/gaps during & after the procedure.
Benefits & Risks
Benefits
Non-invasive, quick, and cost-effective.
Shares critical information for staging and treatment planning.
Detects recurrence earlier.
Risks/Limitations:
Not all testicular cancers produce detectable markers.
Elevated markers can also be visible in non-cancerous conditions (liver disease, hypogonadism, etc.).
Must always be interpreted with other diagnostic tools (ultrasound, CT, biopsy).
FAQs on Tumor Marker Testing
What do elevated AFP or hCG levels mean?
Elevated levels usually indicate the presence of testicular cancer, but further diagnostic tests are needed to confirm.
Can tumor markers alone diagnose testicular cancer?
No. Tumor marker testing supports diagnosis, but should also contribute to the combined effects of imaging and biopsy for confirmation.
How often are tumor markers checked?
They are typically measured before treatment, during therapy, after surgery/chemotherapy, and at regular intervals during follow-up.
Are there other tumor markers apart from AFP and hCG?
Yes. LDH (Lactate Dehydrogenase) is another critical marker that indicates tumor burden and progression.
Can lifestyle or diet affect tumor marker levels?
No, tumor marker levels remain intact from the significant influence of lifestyle or diet. They elevate due to tumor biology.
Why choose Tender Palm Super-Speciality Hospital for Tumor Marker Testing in Lucknow, India?
Tender Palm Super-Speciality Hospital is one of the best hospitals for Tumor Marker Testing in Lucknow, India. Our experienced uro-oncologists use advanced tools to give accurate results, quick diagnosis, and better long-term care. We offer the best evaluation and treatment support with effective and affordable pricing, making the Tumor Marker Testing cost suitable for patients seeking high-quality urology care in Lucknow, India.
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