What is Wilms Tumor?

Wilms Tumor, also known as Nephroblastoma, is a rare type of Kidney Cancer that primarily affects the children. It is the most common type of Kidney Cancer in children and typically occurs in the form of tumor in those aged 3 to 4 years. The tumor develops in the kidneys and can spread to other parts of the body if not treated promptly.

How common is Wilms Tumor?

Wilms Tumor is relatively rare, with around 500 new cases diagnosed in the United States each year. It accounts for about 5% of all childhood Cancers.

Symptoms & Causes

What are the symptoms of Wilms Tumor?

Symptoms of Wilms Tumor can vary but commonly include:-

  • A Noticeable Lump or Mass in the Abdomen.
  • Swelling or Pain in the Abdomen
  • Fever
  • Blood in the Urine (Hematuria)
  • Nausea or Vomiting
  • Loss of Appetite
  • High Blood Pressure

What causes Wilms Tumor?

The exact cause of Wilms Tumor is not well understood, but it is believed to result from a combination of genetic and environmental factors. Certain genetic syndromes and birth defects are associated with an increased risk of developing Wilms Tumor, including:-

  • WAGR Syndrome
  • Beckwith-Wiedemann Syndrome
  • Denys-Drash Syndrome

Diagnosis & Tests

How is Wilms Tumor diagnosed?

The diagnosis of Wilms Tumor typically involves several steps:-

  • Physical Examination - A doctor will check for a swollen abdomen or other signs of the tumor.
  • Imaging Tests - Ultrasound, CT scans, or MRI scans of the abdomen are used to visualize the tumor.
  • Laboratory Tests - Blood and urine tests help evaluate kidney function and detect any abnormalities.
  • Biopsy - In some cases, a sample of the tumor tissue may be taken to confirm the diagnosis.

What role do genetic tests play in diagnosing Wilms Tumor?

Genetic tests can identify mutations associated with Wilms Tumor and help determine the risk of developing the disease, especially in children with a family history of related genetic syndromes.

Management & Treatment

What are the treatment options for Wilms Tumor?

Treatment for Wilms Tumor typically involves a combination of therapies:-

  • Surgery - The primary treatment is the surgical removal of the affected kidney (Nephrectomy). If both kidneys are involved, partial removal may be considered.
  • Chemotherapy - Often used before and/or after surgery to shrink the tumor and kill remaining Cancer cells.
  • Radiation Therapy - May be used in cases where the tumor is large or has spread beyond the kidney.

How effective is the treatment for Wilms Tumor?

Treatment for Wilms Tumor is highly effective, with a high survival rate, especially when the disease is caught early. The five-year survival rate for children with Wilms Tumor is approximately 90%.

Prevention

Can Wilms Tumor be prevented?

Currently, there are no known methods to prevent Wilms Tumor as the exact cause is not fully understood. However, early detection through regular medical check-ups is crucial, especially for children at higher risk due to genetic conditions.

Are there any known risk factors for Wilms Tumor?

Yes, certain genetic syndromes and birth defects increase the risk. Having a family history of Wilms Tumor or related genetic conditions also elevates the risk.

Outlook / Prognosis

What is the prognosis for children diagnosed with Wilms Tumor?

The prognosis for children with Wilms Tumor is generally very good. Early diagnosis and prompt treatment significantly improve the outcome. The overall five-year survival rate is around 90%, but this can vary depending on factors such as the stage of the tumor and the presence of metastasis.

What factors influence the prognosis of Wilms Tumor?

Prognosis is influenced by several factors including:-

  • The Stage of the Tumor at Diagnosis
  • The Tumor's Histology (Favorable vs. Unfavorable)
  • The Child’s Age and Overall Health
  • Response to Treatment

Living With

How can families support a child living with Wilms Tumor?

Support for a child with Wilms Tumor includes:-

  • Ensuring regular follow-up appointments for monitoring and managing any side effects.
  • Providing emotional and psychological support to help the child cope with the illness and treatment.
  • Encouraging a healthy lifestyle with a balanced diet and physical activity as tolerated.

What long-term effects might a child who had Wilms Tumor experience?

While many children recover fully, some may experience long-term effects due to the tumor or its treatment, including:

  • Reduced Kidney Function
  • Heart or Lung Issues from Chemotherapy or Radiation
  • Growth and Development Delays
  • Psychological Impacts Such as Anxiety or Depression

What resources are available for families dealing with Wilms Tumor?

Numerous resources are available, including:-

  • Pediatric Oncology Support Groups
  • Counseling Services
  • Educational resources from organizations like the American Cancer Society and the National Cancer Institute
  • Financial Assistance Programs for Medical Expenses

By understanding Wilms Tumor through these key areas, families can better navigate the challenges and support their child through diagnosis, treatment, and beyond.

Why Tender Palm Super-Specialty Hospital for Wilms Tumor treatment in Lucknow, India?

Tender Palm Hospital has the most experienced team of Uro-oncologists with advanced diagnostics and international standard infection control measures in Lucknow, India. Our specialists have decades of experienced in successfully diagnosing and treating Wilms Tumor in Lucknow, India.

To Seek an Expert Consultation for Wilms Tumor treatment in Lucknow, India:

Call us at +91-9076972161
Email at care@tenderpalm.com

Request an Appointment
Mon - Sat 9:00 AM to 6:00 PM IST

Our Experts

Dr. Feroz Moh. Khan
Dr. Feroz Moh. Khan
Associate Director - Urology

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